ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance Typevgba
DescriptionStreptogramin B Lyase, which can deactivate the target drug by hydrolysis.
Antibiotic Resistancestreptogramin_b
Gene Ontology (GO)Molecular Function
lyase activity [GO:0016829]


Biological Process
streptogramin b resistance [AR:0000050]
drug enzymatic destruction [AR:0001004]
Found in GenusStaphylococcus
COGCOG4257
Description: Streptogramin lyase
Function: Defense mechanisms;

NCBI CDD33980: Vgb
Reference PubMed: 10582867
2) Allignet J, et al. (1988) Nucleotide sequence of a staphylococcal plasmid gene, vgb, encoding a hydrolase inactivating the B components of virginiamycin-like antibiotics.. Plasmid 20(3):271-5 PubMed: 3149758