| Resistance Type | vanxyg |
| Resistance Requirement | vanug vang vanwg vantg vansg vanrg vanyg |
| Description | VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine. |
| Antibiotic Resistance | vancomycin
|
| Gene Ontology (GO) | Molecular Function
D-alanine-D-alanine ligase activity [GO:0008716]
Biological Process
drug target replacement [AR:0001002]
vancomycin resistance [AR:0000028]
|
| Found in Genus | Enterococcus
|
| NCBI CDD | 140944:
|
| Reference | 1) McKessar SJ, et al. (2000) Genetic characterization of vanG, a novel vancomycin resistance locus of Enterococcus faecalis.. Antimicrob Agents Chemother 44(11):3224-8 PubMed: 11036060
PubMed: 16323116
|
