ARDB-Antibiotic Resistance Genes Database

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Resistance Typetetm
DescriptionRibosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Antibiotic Resistancetetracycline
Gene Ontology (GO)Molecular Function
translation elongation factor activity [GO:0003746]


Biological Process
drug target protection [AR:0001003]
tetracycline resistance [AR:0000051]
Found in GenusAcinetobacter
Actinomycetales
Aeromonas
Anaerococcus
Arcanobacterium
Arthrobacter
Bacillus
Brachybacterium
Clostridium
Edwardsiella
Enterococcus
Erysipelothrix
Escherichia
Finegoldia
Flavobacterium
Gardnerella
Klebsiella
Lactobacillus
Lactococcus
Listeria
Mycoplasma
Neisseria
Paenibacillus
Photobacterium
Pseudoalteromonas
Pseudomonas
Shewanella
Sporosarcina
Staphylococcus
Streptococcus
Streptomyces
Ureaplasma
Vibrio
COGCOG480
Description: Translation elongation factors (GTPases)
Function: Translation, ribosomal structure and biogenesis;

NCBI CDD133368
58081: Tet_II
58278: cd01684
58064: Tet_C
30828: FusA
Reference PubMed: 11381101
2) Martin P, et al. (1986) Nucleotide sequence of the tetM tetracycline resistance determinant of the streptococcal conjugative shuttle transposon Tn1545.. Nucleic Acids Res 14(17):7047-58 PubMed: 3020504