ARDB-Antibiotic Resistance Genes Database

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Resistance Typetetj
DescriptionMajor facilitator superfamily transporter, tetracycline efflux pump.
Antibiotic Resistancetetracycline
Gene Ontology (GO)Molecular Function
tetracycline transporter activity [GO:0008493]


Biological Process
major facilitator superfamily (MFS) drug efflux [AR:0010002]
tetracycline resistance [AR:0000051]


Cellular Component
membrane part [GO:0044425]
Found in GenusProteus
COGCOG477
Description: Permeases of the major facilitator superfamily
Function: Carbohydrate transport and metabolism; Amino acid transport and metabolism; Inorganic ion transport and metabolism; General function prediction only;

NCBI CDD116304
119392
Reference1) Magalh„es VD, et al. (1998) A new tetracycline resistance determinant cloned from Proteus mirabilis.. Biochim Biophys Acta 1443(1-2):262-6 PubMed: 9838156
 PubMed: 11381101