ARDB-Antibiotic Resistance Genes Database

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Resistance Typetetc
DescriptionMajor facilitator superfamily transporter, tetracycline efflux pump.
Antibiotic Resistancetetracycline
Gene Ontology (GO)Molecular Function
tetracycline transporter activity [GO:0008493]


Biological Process
major facilitator superfamily (MFS) drug efflux [AR:0010002]
tetracycline resistance [AR:0000051]


Cellular Component
membrane part [GO:0044425]
Found in GenusAcetobacter
Acinetobacter
Aeromonas
Bacillus
Bacteroides
Bifidobacterium
Blautia
Burkholderia
Catonella
Chlamydia
Citrobacter
Clostridiales
Clostridium
Coprococcus
Corynebacterium
Desulfovibrio
Enterobacter
Escherichia
Francisella
Helicobacter
Lactobacillus
Magnetospirillum
Methanobrevibacter
other sequences
Parabacteroides
Populus
Proteus
Providencia
Pseudomonas
Riemerella
Roseburia
Ruminococcaceae
Salmonella
Serratia
Shuttleworthia
Tetraodon
COGCOG477
Description: Permeases of the major facilitator superfamily
Function: Carbohydrate transport and metabolism; Amino acid transport and metabolism; Inorganic ion transport and metabolism; General function prediction only;

NCBI CDD139774
141554
141364
139781
116304
142625
73302: ParA
119392
Reference1) Sutcliffe JG, et al. (1979) Complete nucleotide sequence of the Escherichia coli plasmid pBR322.. Cold Spring Harb Symp Quant Biol 43(0):77-90 PubMed: 383387
 PubMed: 11381101