ARDB-Antibiotic Resistance Genes Database

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Resistance Typetet38
DescriptionMajor facilitator superfamily transporter, tetracycline efflux pump.
Antibiotic Resistancetetracycline
Gene Ontology (GO)Molecular Function
tetracycline transporter activity [GO:0008493]


Biological Process
major facilitator superfamily (MFS) drug efflux [AR:0010002]
tetracycline resistance [AR:0000051]


Cellular Component
membrane part [GO:0044425]
Found in GenusStaphylococcus
COGCOG477
Description: Permeases of the major facilitator superfamily
Function: Carbohydrate transport and metabolism; Amino acid transport and metabolism; Inorganic ion transport and metabolism; General function prediction only;

NCBI CDD129794
Reference PubMed: 11381101
2) Hiramatsu K, et al. (1997) Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin.. Lancet 350(9092):1670-3 PubMed: 9400512