ARDB-Antibiotic Resistance Genes Database

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Resistance Typetet32
DescriptionRibosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Antibiotic Resistancetetracycline
Gene Ontology (GO)Molecular Function
translation elongation factor activity [GO:0003746]


Biological Process
drug target protection [AR:0001003]
tetracycline resistance [AR:0000051]
Found in GenusAbiotrophia
Acidaminococcus
Anaerotruncus
Blautia
Clostridiaceae
Escherichia
Eubacterium
Holdemania
Streptococcus
COGCOG480
Description: Translation elongation factors (GTPases)
Function: Translation, ribosomal structure and biogenesis;

NCBI CDD133368
58081: Tet_II
58278: cd01684
58064: Tet_C
30828: FusA
Reference PubMed: 11381101
2) Melville CM, et al. (2001) Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens.. Antimicrob Agents Chemother 45(11):3246-9 PubMed: 11600392