ARDB-Antibiotic Resistance Genes Database

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Resistance Typesul3
DescriptionSulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
Antibiotic Resistancesulfonamide
Gene Ontology (GO)Molecular Function
dihydropteroate synthase activity [GO:0004156]


Biological Process
drug target replacement [AR:0001002]
sulfonamide resistance [AR:0000031]
Found in GenusEscherichia
Salmonella
NCBI CDD29545: DHPS
Reference1) Perreten V, et al. (2003) A new sulfonamide resistance gene (sul3) in Escherichia coli is widespread in the pig population of Switzerland.. Antimicrob Agents Chemother 47(3):1169-72 PubMed: 12604565
 PubMed: 11432417