ARDB-Antibiotic Resistance Genes Database

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Resistance Typesul2
DescriptionSulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
Antibiotic Resistancesulfonamide
Gene Ontology (GO)Molecular Function
dihydropteroate synthase activity [GO:0004156]


Biological Process
drug target replacement [AR:0001002]
sulfonamide resistance [AR:0000031]
Found in GenusAcinetobacter
Actinobacillus
Aeromonas
Aliivibrio
Avibacterium
Bibersteinia
Enterobacter
Erwinia
Escherichia
Gammaproteobacteria
Haemophilus
Klebsiella
Leucobacter
Mannheimia
Microbacterium
Neisseria
Ochrobactrum
Pasteurella
Photobacterium
Pseudomonas
Psychrobacter
Riemerella
Salmonella
Shigella
Stenotrophomonas
Vibrio
Yersinia
NCBI CDD29545: DHPS
Reference1) Oka A, et al. (1981) Nucleotide sequence of the kanamycin resistance transposon Tn903.. J Mol Biol 147(2):217-26 PubMed: 6270337
 PubMed: 11432417