ARDB-Antibiotic Resistance Genes Database

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Resistance Typesul1
DescriptionSulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
Antibiotic Resistancesulfonamide
Gene Ontology (GO)Molecular Function
dihydropteroate synthase activity [GO:0004156]


Biological Process
drug target replacement [AR:0001002]
sulfonamide resistance [AR:0000031]
Found in GenusAchromobacter
Acinetobacter
Aeromonas
Bordetella
Citrobacter
Corynebacterium
Enterobacter
Escherichia
Klebsiella
Kluyvera
Microbacterium
Morganella
Mycobacterium
Ochrobactrum
Proteus
Pseudomonas
Riemerella
Salmonella
Shigella
Syntrophus
Vibrio
Yersinia
NCBI CDD140522
29545: DHPS
Reference1) Swift G, et al. (1981) DNA sequence of a plasmid-encoded dihydrofolate reductase.. Mol Gen Genet 181(4):441-7 PubMed: 7022127
 PubMed: 11432417