ARDB-Antibiotic Resistance Genes Database

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Resistance Typesrmb
DescriptionABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Antibiotic Resistancelincosamide
macrolide
streptogramin_b
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]
ABC-type efflux porter activity [GO:0015427]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]
lincomycin resistance [AR:0000046]
macrolide resistance [AR:0000033]
streptogramin b resistance [AR:0000050]


Cellular Component
membrane part [GO:0044425]
Found in GenusStreptomyces
COGCOG488
Description: ATPase components of ABC transporters with duplicated ATPase domains
Function: General function prediction only;

NCBI CDD72980: ABCF_EF-3
30834: Uup
Reference1) Geistlich M, et al. (1992) Characterization of a novel regulatory gene governing the expression of a polyketide synthase gene in Streptomyces ambofaciens.. Mol Microbiol 6(14):2019-29 PubMed: 1508047
 PubMed: 10582867