ARDB-Antibiotic Resistance Genes Database

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Resistance Typesmea
Resistance Requirementsmec    smeb    
DescriptionResistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Antibiotic Resistancefluoroquinolone
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]
fluoroquinolone resistance [AR:0000026]


Cellular Component
membrane part [GO:0044425]
Found in GenusStenotrophomonas
Xanthomonas
COGCOG1566
Description: Multidrug resistance efflux pump
Function: Defense mechanisms;

NCBI CDD137559
Reference1) Zhang L, et al. (2001) SmeDEF multidrug efflux pump contributes to intrinsic multidrug resistance in Stenotrophomonas maltophilia.. Antimicrob Agents Chemother 45(12):3497-503 PubMed: 11709330