ARDB-Antibiotic Resistance Genes Database

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Resistance Typepbp2b
DescriptionThe enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
Antibiotic Resistancepenicillin
Found in GenusNeisseria
COGCOG768
Description: Cell division protein FtsI/penicillin-binding protein 2
Function: Cell wall/membrane/envelope biogenesis;

NCBI CDD31111: FtsI
112527
120336
Reference1) Spratt BG, et al. (1988) Hybrid penicillin-binding proteins in penicillin-resistant strains of Neisseria gonorrhoeae.. Nature 332(6160):173-6 PubMed: 3126399