ARDB-Antibiotic Resistance Genes Database

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Resistance Typepbp1a
DescriptionThe enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
Antibiotic Resistancepenicillin
Found in GenusHaemophilus
COGCOG5009
Description: Membrane carboxypeptidase/penicillin-binding protein
Function: Cell wall/membrane/envelope biogenesis;

NCBI CDD34614: MrcA
141990
138687
120336
Reference1) Tomb JF, et al. (1991) Nucleotide sequence of a cluster of genes involved in the transformation of Haemophilus influenzae Rd.. Gene 104(1):1-10 PubMed: 1916268