ARDB-Antibiotic Resistance Genes Database

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Resistance Typemepa
DescriptionMulti antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
Antibiotic Resistancetigecycline
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]


Biological Process
tigecycline resistance [AR:0000030]
Found in GenusStaphylococcus
COGCOG534
Description: Na+-driven multidrug efflux pump
Function: Defense mechanisms;

NCBI CDD30880: NorM
110551
Reference1) Hiramatsu K, et al. (1997) Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin.. Lancet 350(9092):1670-3 PubMed: 9400512