ARDB-Antibiotic Resistance Genes Database

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Resistance Typelmra
DescriptionABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Antibiotic Resistancelincomycin
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]
ABC-type efflux porter activity [GO:0015427]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]
lincomycin resistance [AR:0000046]
macrolide resistance [AR:0000033]
streptogramin b resistance [AR:0000050]


Cellular Component
membrane part [GO:0044425]
Found in GenusStreptomyces
NCBI CDD129794
119392
Reference PubMed: 10582867
2) Zhang HZ, et al. (1992) Molecular cloning and characterization of two lincomycin-resistance genes, lmrA and lmrB, from Streptomyces lincolnensis 78-11.. Mol Microbiol 6(15):2147-57 PubMed: 1328813