ARDB-Antibiotic Resistance Genes Database

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Resistance Typeksga
DescriptionSpecifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
Antibiotic Resistancekasugamycin
Found in GenusCitrobacter
Cronobacter
Enterobacter
Escherichia
Klebsiella
Pectobacterium
Photorhabdus
Providencia
Salmonella
Serratia
Shigella
Yersinia
COGCOG30
Description: Dimethyladenosine transferase (rRNA methylation)
Function: Translation, ribosomal structure and biogenesis;

NCBI CDD142332
Reference1) Musso R, et al. (1977) Nucleotide sequence of the operator-promoter region of the galactose operon of Escherichia coli.. Proc Natl Acad Sci U S A 74(1):106-10 PubMed: 319453