ARDB-Antibiotic Resistance Genes Database

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Resistance Typefosb
DescriptionGlutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
Antibiotic Resistancefosfomycin
Gene Ontology (GO)Molecular Function
glutathione transferase activity [GO:0004364]


Biological Process
fosfomycin resistance [AR:0000025]
drug enzymatic destruction [AR:0001004]
Found in GenusBacillus
Geobacillus
Lysinibacillus
Oceanobacillus
Siphoviridae
Staphylococcus
COGCOG346
Description: Lactoylglutathione lyase and related lyases
Function: Amino acid transport and metabolism;

NCBI CDD140684
Reference PubMed: 17704766