ARDB-Antibiotic Resistance Genes Database

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Resistance Typefosa
DescriptionGlutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
Antibiotic Resistancefosfomycin
Gene Ontology (GO)Molecular Function
glutathione transferase activity [GO:0004364]


Biological Process
fosfomycin resistance [AR:0000025]
drug enzymatic destruction [AR:0001004]
Found in GenusEnterobacter
Serratia
NCBI CDD140684
Reference1) Navas J, et al. (1990) Nucleotide sequence and intracellular location of the product of the fosfomycin resistance gene from transposon Tn2921.. Antimicrob Agents Chemother 34(10):2016-8 PubMed: 1963292