ARDB-Antibiotic Resistance Genes Database

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Resistance Typeerea
DescriptionErythromycin esterase, which can inactivate erythromycin by lactone ring cleavage.
Antibiotic Resistanceerythromycin
Gene Ontology (GO)Molecular Function
hydrolase activity, acting on ester bonds [GO:0016788]


Biological Process
erythromycin resistance [AR:0000006]
drug enzymatic destruction [AR:0001004]
Found in GenusAchromobacter
Aeromonas
Enterobacter
Escherichia
Klebsiella
Providencia
Pseudomonas
Salmonella
Vibrio
NCBI CDD113894
Reference PubMed: 10582867
2) Ounissi H, et al. (1985) Nucleotide sequence of the gene ereA encoding the erythromycin esterase in Escherichia coli.. Gene 35(3):271-8 PubMed: 3899861