ARDB-Antibiotic Resistance Genes Database

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Resistance Typedfrb6
DescriptionGroup B drug-insensitive R67 dihydrofolate reductase, which can not be inhibited by trimethoprim.
Antibiotic Resistancetrimethoprim
Gene Ontology (GO)Molecular Function
dihydrofolate reductase activity [GO:0004146]


Biological Process
trimethoprim resistance [AR:0000010]
Found in GenusSalmonella
NCBI CDD115119
Reference1) Collis CM, et al. (1995) Expression of antibiotic resistance genes in the integrated cassettes of integrons.. Antimicrob Agents Chemother 39(1):155-62 PubMed: 7695299
 PubMed: 11432417