ARDB-Antibiotic Resistance Genes Database

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Resistance Typedfra25
DescriptionGroup A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Antibiotic Resistancetrimethoprim
Gene Ontology (GO)Molecular Function
dihydrofolate reductase activity [GO:0004146]


Biological Process
trimethoprim resistance [AR:0000010]
Found in GenusCitrobacter
Salmonella
NCBI CDD29264: DHFR
Reference1) Peirano G, et al. (2006) Occurrence of integrons and antimicrobial resistance genes among Salmonella enterica from Brazil.. J Antimicrob Chemother 58(2):305-9 PubMed: 16782743
 PubMed: 11432417