ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance Typedfra24
DescriptionGroup A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Antibiotic Resistancetrimethoprim
Gene Ontology (GO)Molecular Function
dihydrofolate reductase activity [GO:0004146]


Biological Process
trimethoprim resistance [AR:0000010]
Found in GenusEscherichia
NCBI CDD29264: DHFR
Reference1) Grape M, et al. (2007) Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.. Antimicrob Agents Chemother 51(5):1863-4 PubMed: 17307981
 PubMed: 11432417