ARDB-Antibiotic Resistance Genes Database

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Resistance Typedfra23
DescriptionGroup A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Antibiotic Resistancetrimethoprim
Gene Ontology (GO)Molecular Function
dihydrofolate reductase activity [GO:0004146]


Biological Process
trimethoprim resistance [AR:0000010]
Found in GenusSalmonella
Vibrio
NCBI CDD29264: DHFR
Reference1) Villa L, et al. (2005) Integrons and transposons on the Salmonella enterica serovar typhimurium virulence plasmid.. Antimicrob Agents Chemother 49(3):1194-7 PubMed: 15728925
 PubMed: 11432417