ARDB-Antibiotic Resistance Genes Database

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Resistance Typedfra17
DescriptionGroup A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Antibiotic Resistancetrimethoprim
Gene Ontology (GO)Molecular Function
dihydrofolate reductase activity [GO:0004146]


Biological Process
trimethoprim resistance [AR:0000010]
Found in GenusAcinetobacter
Enterobacter
Escherichia
Klebsiella
Kluyvera
Pseudomonas
Salmonella
Serratia
Shigella
Staphylococcus
NCBI CDD29264: DHFR
Reference1) White PA, et al. (2000) Characterisation of two new gene cassettes, aadA5 and dfrA17.. FEMS Microbiol Lett 182(2):265-9 PubMed: 10620677
 PubMed: 11432417