ARDB-Antibiotic Resistance Genes Database

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Resistance Typecml_e6
DescriptionMajor facilitator superfamily transporter, chloramphenicol efflux pump.
Antibiotic Resistancechloramphenicol
Gene Ontology (GO)Molecular Function
chloramphenicol transporter activity [GO:0042896]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]


Cellular Component
membrane part [GO:0044425]
Found in GenusStreptomyces
NCBI CDD116304
119392
Reference1) Mosher RH, et al. (1995) Inactivation of chloramphenicol by O-phosphorylation. A novel resistance mechanism in Streptomyces venezuelae ISP5230, a chloramphenicol producer.. J Biol Chem 270(45):27000-6 PubMed: 7592948