ARDB-Antibiotic Resistance Genes Database

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Resistance Typecml_e5
DescriptionMajor facilitator superfamily transporter, chloramphenicol efflux pump.
Antibiotic Resistancechloramphenicol
Gene Ontology (GO)Molecular Function
chloramphenicol transporter activity [GO:0042896]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]


Cellular Component
membrane part [GO:0044425]
Found in GenusStreptomyces
COGCOG2814
Description: Arabinose efflux permease
Function: Carbohydrate transport and metabolism;

NCBI CDD142625
32643: AraJ
Reference1) Dittrich W, et al. (1991) An amplifiable and deletable chloramphenicol-resistance determinant of Streptomyces lividans 1326 encodes a putative transmembrane protein.. Mol Microbiol 5(11):2789-97 PubMed: 1779766