ARDB-Antibiotic Resistance Genes Database

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Resistance Typecml_e1
DescriptionMajor facilitator superfamily transporter, chloramphenicol efflux pump.
Antibiotic Resistancechloramphenicol
Gene Ontology (GO)Molecular Function
chloramphenicol transporter activity [GO:0042896]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]


Cellular Component
membrane part [GO:0044425]
Found in GenusAcinetobacter
Aeromonas
Enterobacter
Escherichia
Klebsiella
Proteobacteria
Pseudomonas
Salmonella
Serratia
Staphylococcus
NCBI CDD129793
119392
Reference1) Bissonnette L, et al. (1991) Characterization of the nonenzymatic chloramphenicol resistance (cmlA) gene of the In4 integron of Tn1696: similarity of the product to transmembrane transport proteins.. J Bacteriol 173(14):4493-502 PubMed: 1648560