ARDB-Antibiotic Resistance Genes Database

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Resistance Typecatb2
DescriptionGroup B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
Antibiotic Resistancechloramphenicol
Gene Ontology (GO)Molecular Function
chloramphenicol O-acetyltransferase activity [GO:0008811]


Biological Process
chloramphenicol resistance [AR:0000002]
drug enzymatic destruction [AR:0001004]
Found in GenusAcinetobacter
Aeromonas
Bordetella
Escherichia
Klebsiella
Pasteurella
Pseudomonas
Salmonella
NCBI CDD100040
Reference1) Parent R, et al. (1992) The chloramphenicol acetyltransferase gene of Tn2424: a new breed of cat.. J Bacteriol 174(9):2891-7 PubMed: 1314803