ARDB-Antibiotic Resistance Genes Database

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Resistance Typecata8
DescriptionGroup A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Antibiotic Resistancechloramphenicol
Gene Ontology (GO)Molecular Function
chloramphenicol O-acetyltransferase activity [GO:0008811]


Biological Process
chloramphenicol resistance [AR:0000002]
drug enzymatic destruction [AR:0001004]
Found in GenusEnterococcus
Lactococcus
Listeria
Staphylococcus
NCBI CDD141349
Reference1) Schwarz S, et al. (1991) Nucleotide sequence and phylogeny of a chloramphenicol acetyltransferase encoded by the plasmid pSCS7 from Staphylococcus aureus.. Antimicrob Agents Chemother 35(8):1551-6 PubMed: 1929326