ARDB-Antibiotic Resistance Genes Database

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Resistance Typecata4
DescriptionGroup A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Antibiotic Resistancechloramphenicol
Gene Ontology (GO)Molecular Function
chloramphenicol O-acetyltransferase activity [GO:0008811]


Biological Process
chloramphenicol resistance [AR:0000002]
drug enzymatic destruction [AR:0001004]
Found in GenusProteus
COGCOG4845
Description: Chloramphenicol O-acetyltransferase
Function: Defense mechanisms;

NCBI CDD141349
Reference1) Charles IG, et al. (1985) Nucleotide sequence analysis of the cat gene of Proteus mirabilis: comparison with the type I (Tn9) cat gene.. J Bacteriol 164(1):123-9 PubMed: 3900035