ARDB-Antibiotic Resistance Genes Database

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Resistance Typebmr
DescriptionMajor facilitator superfamily transporter. Multidrug resistance efflux pump.
Antibiotic Resistancechloramphenicol
fluoroquinolone
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]


Biological Process
chloramphenicol resistance [AR:0000002]
major facilitator superfamily (MFS) drug efflux [AR:0010002]
fluoroquinolone resistance [AR:0000026]


Cellular Component
membrane part [GO:0044425]
Found in GenusBacillus
COGCOG477
Description: Permeases of the major facilitator superfamily
Function: Carbohydrate transport and metabolism; Amino acid transport and metabolism; Inorganic ion transport and metabolism; General function prediction only;

NCBI CDD142625
116304
119392
Reference1) Neyfakh AA, et al. (1991) Efflux-mediated multidrug resistance in Bacillus subtilis: similarities and dissimilarities with the mammalian system.. Proc Natl Acad Sci U S A 88(11):4781-5 PubMed: 1675788