ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl3_vim
DescriptionClass B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecarbapenem
cephalosporin
cephamycin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusAchromobacter
Acinetobacter
Aeromonas
Enterobacter
Escherichia
Klebsiella
Morganella
Proteus
Providencia
Pseudomonas
Serratia
NCBI CDD140710
Reference1) Lauretti L, et al. (1999) Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate.. Antimicrob Agents Chemother 43(7):1584-90 PubMed: 10390207