ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl3_shw
DescriptionClass B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecarbapenem
cephalosporin
cephamycin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusShewanella
NCBI CDD140710
Reference1) Poirel L, et al. (2005) Genetic and biochemical characterization of the chromosome-encoded class B beta-lactamases from Shewanella livingstonensis (SLB-1) and Shewanella frigidimarina (SFB-1).. J Antimicrob Chemother 55(5):680-5 PubMed: 15772146