ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl3_l
DescriptionClass B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecarbapenem
cephalosporin
cephamycin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusStenotrophomonas
Zea
COGCOG491
Description: Zn-dependent hydrolases, including glyoxylases
Function: General function prediction only;

NCBI CDD140710
Reference1) Bicknell R, et al. (1985) The production and molecular properties of the zinc beta-lactamase of Pseudomonas maltophilia IID 1275.. Biochem J 229(3):791-7 PubMed: 3931629