ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl3_gim
DescriptionClass B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecarbapenem
cephalosporin
cephamycin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusPseudomonas
NCBI CDD140710
Reference1) Castanheira M, et al. (2004) Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase.. Antimicrob Agents Chemother 48(12):4654-61 PubMed: 15561840