ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl3_cpha
DescriptionClass B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecarbapenem
cephalosporin
cephamycin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusAeromonas
NCBI CDD140710
Reference1) Massidda O, et al. (1991) The Aeromonas hydrophila cphA gene: molecular heterogeneity among class B metallo-beta-lactamases.. J Bacteriol 173(15):4611-7 PubMed: 1856163