ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2f_nmca
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecarbapenem
cephalosporin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusEnterobacter
NCBI CDD141062
Reference1) Naas T, et al. (1994) Analysis of a carbapenem-hydrolyzing class A beta-lactamase from Enterobacter cloacae and of its LysR-type regulatory protein.. Proc Natl Acad Sci U S A 91(16):7693-7 PubMed: 8052644