ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2e_fpm
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecephalosporin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusProteus
NCBI CDD141062
Reference1) Péduzzi J, et al. (1994) Chromosomally encoded cephalosporin-hydrolyzing beta-lactamase of Proteus vulgaris RO104 belongs to Ambler's class A.. Biochim Biophys Acta 1207(1):31-9 PubMed: 8043607