ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2e_cfxa
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecephalosporin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusBacteroides
Capnocytophaga
Parabacteroides
Prevotella
NCBI CDD141062
Reference1) Parker AC, et al. (1993) Genetic and biochemical analysis of a novel Ambler class A beta-lactamase responsible for cefoxitin resistance in Bacteroides species.. Antimicrob Agents Chemother 37(5):1028-36 PubMed: 8517690