ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2e_cbla
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecephalosporin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusBacteroides
COGCOG2367
Description: Beta-lactamase class A
Function: Defense mechanisms;

NCBI CDD141062
Reference1) Smith CJ, et al. (1994) Molecular and genetic analysis of the Bacteroides uniformis cephalosporinase gene, cblA, encoding the species-specific beta-lactamase.. Antimicrob Agents Chemother 38(8):1711-5 PubMed: 7985999