ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2d_oxa2
DescriptionClass D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecloxacillin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusAchromobacter
Acinetobacter
Aeromonas
Bordetella
Burkholderia
Corynebacterium
Enterobacter
Escherichia
Klebsiella
Morganella
Pseudomonas
Salmonella
Vibrio
NCBI CDD120336
Reference1) Holland S, et al. (1984) Improved purification and characterization of the OXA-2 beta-lactamase.. Biochem J 224(3):1009-13 PubMed: 6335398