ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2d_oxa1
DescriptionClass D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecloxacillin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusAcinetobacter
Citrobacter
Escherichia
Klebsiella
Kluyvera
Pseudomonas
Salmonella
Serratia
Shigella
NCBI CDD120336
Reference1) Ouellette M, et al. (1987) Precise insertion of antibiotic resistance determinants into Tn21-like transposons: nucleotide sequence of the OXA-1 beta-lactamase gene.. Proc Natl Acad Sci U S A 84(21):7378-82 PubMed: 2823258