ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2d_moxa
DescriptionClass D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecloxacillin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusStreptomyces
NCBI CDD141062
Reference1) De Meester F, et al. (1987) The active sites of the beta-lactamases of Streptomyces cacaoi and Streptomyces albus G.. Biochem J 244(2):427-32 PubMed: 2822004