ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2c_bro
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecarbenicillin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusAcinetobacter
Oligella
Proteus
NCBI CDD141062
Reference1) Paul G, et al. (1989) Novel carbenicillin-hydrolyzing beta-lactamase (CARB-5) from Acinetobacter calcoaceticus var. anitratus.. FEMS Microbiol Lett 50(1-2):45-50 PubMed: 2786828