ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2be_oxy1
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancemonobactam
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusKlebsiella
NCBI CDD141062
Reference1) Arakawa Y, et al. (1989) Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics.. Antimicrob Agents Chemother 33(1):63-70 PubMed: 2653216