ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2be_ctxm
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistanceceftazidime
cephalosporin_i
cephalosporin_ii
cephalosporin_iii
monobactam
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusAcinetobacter
Citrobacter
Enterobacter
Escherichia
Klebsiella
Kluyvera
Morganella
Pantoea
Proteus
Providencia
Pseudomonas
Raoultella
Salmonella
Serratia
Shigella
Vibrio
NCBI CDD141062
Reference1) Matsumoto Y, et al. (1988) Novel plasmid-mediated beta-lactamase from Escherichia coli that inactivates oxyimino-cephalosporins.. Antimicrob Agents Chemother 32(8):1243-6 PubMed: 3056257