ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2b_rob
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecephalosporin
penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusActinobacillus
Haemophilus
Mannheimia
Pasteurella
NCBI CDD141062
Reference1) Juteau JM, et al. (1990) Sequence analysis and evolutionary perspectives of ROB-1 beta-lactamase.. Antimicrob Agents Chemother 34(7):1354-9 PubMed: 2201253