ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2a_pc
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancepenicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusEnterococcus
Staphylococcus
COGCOG2367
Description: Beta-lactamase class A
Function: Defense mechanisms;

NCBI CDD141062
Reference1) Ambler RP, et al. (1975) The amino acid sequence of Staphylococcus aureus penicillinase.. Biochem J 151(2):197-218 PubMed: 1218078