ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2a_iii2
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancepenicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusBacillus
NCBI CDD141062
Reference1) Meadway RJ, et al. (1969) The amino acid sequence of penicillinase from Bacillus licheniformis.. Biochem J 115(3):12P-13P PubMed: 5353499